[Hosokawa Micron] New hair care and skin care technology products from Japan. Our original nano-technology (PLGA capsule) supports hair growth and beautiful skin.

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Hosokawa Micron, a world leader in nanotechnology founded 106 years ago, has successfully applied the PLGA capsule technology for medical use developed in a large-scale national project to hair growth products and cosmetics and commercialized them.

PLGA nano capsules have realized the DDS (Drug Delivery System) challenge that has long been required in the medical field: "to safely deliver the necessary ingredients in the necessary quantities to the necessary places. The ultra-micro capsules, 140 nanometers in diameter, quickly penetrate to the target site and continue to supply the encapsulated ingredients with pinpoint accuracy for an extended period of time.

We are the first company to successfully apply the nanocapsules with this excellent DDS concept (safety, penetration, and sustainability) to the cosmetics field, and have launched the innovative hair-growth agent brand NanoImpact® and the cosmetics brands NanoCrysphere® and ExquiRoutine® to ensure the penetration of useful ingredients into all parts of the scalp and skin. ExquiRoutine® was born.

Hosokawa Micron introduces hair care and skin care products containing this one and only PLGA capsule.

We are currently looking for sales partners in ASEAN countries (some excluded).

Delivering the necessary ingredients where they are needed, in the right quantities.


No matter how excellent an ingredient may be, if it is not delivered, it will not be effective.

Hosokawa Micron has developed PLGA (lactic acid/glycolic acid copolymer) capsules with DDS functionality, which can efficiently deliver useful ingredients to the inside of the skin (stratum corneum) and pores (papilla), where they can be sustained and released. In other words, the role of PLGA capsules is to maximize the effects of the active ingredients where they are needed.

What are PLGA capsules?


1. permeability: allows useful ingredients to penetrate to where they are needed.
PLGA capsules are 140 nanometers in diameter (two millionths of a pore's cross-sectional area) and are compatible with both water and oil, allowing them to quickly penetrate the horny layer and pores where sweat and sebum are abundant, resulting in the efficient delivery of useful ingredients enclosed in PLGA capsules.

2. persistence: Long-lasting effects of useful ingredients.
PLGA capsules that penetrate into the skin and pores continue to release the encapsulated useful ingredients little by little through continuous hydrolysis of PLGA, thus sustaining the effects of the useful ingredients for a long time. In addition, the AHA components (lactic acid and glycolic acid) produced as a result of PLGA's own degradation have the function of stimulating the turnover of the old stratum corneum, thereby supporting skin metabolism.

Safety: Made from safe and secure materials that do not accumulate in the body.
PLGA that penetrates into the skin and pores is hydrolyzed to lactic acid and glycolic acid, and finally metabolically decomposed into water and carbon dioxide and discharged from the body, making it a safe and secure capsule that does not accumulate in the body.

Functional cosmetics containing PLGA capsules


In 2000, Hosokawa Micron proved the functionality, safety, and stability of PLGA capsules through a large-scale national project (NEDO Basic Technology Research Promotion Project), and successfully developed cosmetics (NanoCrysphere®, launched in 2004) and hair growth products (NanoImpact®, launched in 2006) as the result of the project. The company has successfully developed cosmetics (NanoCrysphere®, launched in 2004) and hair growth products (NanoImpact®, launched in 2006), and has received numerous academic, invention, and industry awards.

Both brands are sold online in Japan through our sales subsidiary (Hosokawa Micron Cosmetics), and the NanoImpact® hair-growth agent series has been our best-selling product with sales exceeding 2 million units since its launch in 2006.
In 2020, the ExquiRoutine® skincare series was launched as an original brand developed jointly with a Chinese partner company.

Currently, Hosokawa Micron is expanding sales channels for its original brand into overseas markets, and the brand is highly acclaimed both in Japan and overseas.

Brand List



NanoImpact®] Hair care brand
1. Co17 (men's hair growth products)
2. Co17 LADY (hair growth products for women)
3. SHAMPOO (shampoo)
4 CONDITIONER (conditioner)
Grand Cru (high-grade hair-growth agent)

NanoCrysphere®] skincare brands
1. prime foam 100 (facial cleansing foam)
2. prime lotion 100 (lotion)
3. prime serum 100 (serum)
4. prime cream 100 (moisturizing cream)
5. perfect jelly (gel serum)
6. powdery moist plus
7. puacnes gel
8. eyelash serum
9. eye cream

ExquiRoutine ®] skincare brands
1. RedAdvantage series Lotion Ⅲ (lotion)
2. RedAdvantage series Lotion mask Ⅱ (gel serum)
3. RedAdvantage series serum Ⅰ (serum)
RedAdvantage series serum mask Ⅰ(serum sheet)

(Note) The above information is current as of April 2022 and is subject to change without notice.

For inquiries regarding products and technologies or for business meetings, please contact us through the website below.
https://hosokawamicron-cosmetics-b2b.com/contact/
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